Muscle Contracture following Injury

Spasticity and muscle contracture following stroke.

It has become increasingly recognized that the major functional deficits following brain damage are largely due to "negative' features such as weakness and loss of dexterity rather than spasticity. A variety of studies suggest that spasticity is a distinct problem and separate from the loss of dexterity, but that it may be implicated in the formation of muscle contracture and even in the recove...

Contracture of phosphorylase deficient muscle.

Muscle Enzyme Changes following a Whiplash Injury

This study was a prospective evaluation of serial muscle enzyme changes in 25 consecutive patients who were suffering from neck pain following a rear end motor vehicle accident. The objectives were to assess if muscle damage occurs and to quantify it following a whiplash injury. It is often stated that a whiplash injury is a soft tissue injury consisting of damage to the muscles and ligaments o...

Injury to skeletal muscle of mice following acute and sub-acute pregabalin exposure

Objective(s): Pregabalin (PGB) is a new antiepileptic drug that has received FDA approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. This study was undertaken to evaluate the possible adverse effects of PGB on the muscular system of mice. Materials and Methods: To evaluate the effect of PGB on skeletal...

Physical rehabilitation improves muscle function following volumetric muscle loss injury

BACKGROUND Given the clinical practice of prescribing physical rehabilitation for the treatment of VML injuries, the present study examined the functional and histomorphological adaptations in the volumetric muscle loss (VML) injured muscle to physical rehabilitation. METHODS Tibialis anterior muscle VML injury was created in Lewis rats (n = 32), and were randomly assigned to either sedentary...